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Central Line-Associated Bloodstream Infection (CLABSI)

What do I need to know about CLABSI?

A central line-associated bloodstream infection, or CLABSI, is a type of infection of the blood that is associated with the use of a central line (central venous catheter). A central line is a tube inserted into a major vein in a patient’s chest, neck, arm, or groin that is used to take blood or to give medications. Central lines are usually in place for a long period of time and are very common in healthcare facility intensive care units. Germs (bacteria) that are present on or in the central line can enter the bloodstream and cause a CLABSI.

The Joint Commission

For more information on The Joint Commission and the Central Line-Associated Bloodstream Infections Toolkit and Monograph please visit https://www.jointcommission.org/resources/patient-safety-topics/infection-prevention-and-control/central-line-associated-bloodstream-infections-toolkit-and-monograph/.

Routes for Central Venous Catheter Contamination with Microorganisms

Additional Resources


Indiana Department of Health

Indiana Hospital Association (IHA)

Agency for Healthcare Research and Quality (AHRQ)

Page reviewed and updated: March 2022