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National Overdose Data Reports and Briefs

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National Reports

Drug Overdose Deaths Involving Stimulants — United States, January 2018–June 2024. Morbidity and Mortality Weekly Report August 28, 2025.

Trends in Suspected Fentanyl-Involved Nonfatal Overdose Emergency Department Visits, by Age Group, Sex, and Race and Ethnicity — United States, October 2020–March 2024. Morbidity and Mortality Weekly Report May 8, 2025.

Overdoses Involving Medetomidine Mixed with Opioids — Chicago, Illinois, May 2024. Morbidity and Mortality Weekly Report May 1, 2025.

Controlled Substance Prescribing Patterns Among Fatal Overdose Decedents with an Opioid, Stimulant, or Both Contributing to Death — Pennsylvania, 2017–2022. Morbidity and Mortality Weekly Report April 10, 2025.

Synthetic Opioid and Stimulant Co-Involved Overdose Deaths by Occupation and Industry — United States, 2022. Morbidity and Mortality Weekly Report March 27, 2025.

Detection of Illegally Manufactured Fentanyls and Carfentanil in Drug Overdose Deaths — United States, 2021–2024. Morbidity and Mortality Weekly Report December 5, 2024.

Detection of Medetomidine Among Patients Evaluated in Emergency Departments for Suspected Opioid Overdoses — Missouri, Colorado, and Pennsylvania, September 2020– December 2023.  Morbidity and Mortality Weekly Report August 1, 2024

Reported Xylazine Use Among Adults Aged ≥18 Years Evaluated for Substance Use Treatment — United States, July 2022–September 2023. Morbidity and Mortality Weekly Report July 4, 2024

Routes of Drug Use Among Drug Overdose Deaths — United States, 2020–2022. Morbidity and Mortality Weekly Report February 15, 2024

Drug Overdose Deaths with Evidence of Counterfeit Pill Use — United States, July 2019–December 2021. Morbidity and Mortality Weekly Report September 1, 2023

Illicitly Manufactured Fentanyl–Involved Overdose Deaths with Detected Xylazine — United States, January 2019–June 2022. Morbidity and Mortality Weekly Report June 30, 2023

Drug Overdose Deaths Among Persons Aged 10–19 Years — United States, July 2019–December 2021.  Morbidity and Mortality Weekly Report December 16, 2022

A qualitative assessment of circumstances surrounding drug overdose deaths during the early stages of the COVID-19 pandemic. SUDORS Data Brief 2, August 2022

Overdose Deaths Involving Para-fluorofentanyl — United States, July 2020–June 2021.  Notes from the Field, Morbidity and Mortality Weekly Report September 30, 2022

Vital Signs: Drug Overdose Deaths, by Selected Socio-demographic and Social Determinants of Health Characteristics — 25 States and the District of Columbia, 2019–2020. Morbidity and Mortality Weekly Report July 22, 2022

Drug Overdose Deaths in 28 States and the District of Columbia: 2020 Data from the State Unintentional Drug Overdose Reporting System. SUDORS Data Brief 1, June 2022

Characteristics of Adults Aged ≥ 18 Years Evaluated for Substance Use and Treatment Planning - United States 2019.  Morbidity and Mortality Weekly Report June 10, 2022

Notes from the Field: Xylazine Detection and Involvement in Drug Overdose Deaths — United States, 2019. Morbidity and Mortality Weekly Report September 17, 2021

Trends in Nonfatal and Fatal Overdoses Involving Benzodiazepines — 38 States and the District of Columbia, 2019–2020. Morbidity and Mortality Weekly Report August 27, 2021

Vital Signs: Characteristics of Drug Overdose Deaths Involving Opioids and Stimulants — 24 States and the District of Columbia, January–June 2019. Morbidity and Mortality Weekly Report September 4, 2020

Variation in Adult Outpatient Opioid Prescription Dispensing by Age and Sex — United States, 2008–2018. Morbidity and Mortality Weekly Report March 20, 2020.

Contact Information:
Allison Martin
Drug Overdose Prevention Epidemiologist, Division of Trauma and Injury Prevention