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National Drug Overdose Data

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View a wide range of national drug overdose statistics at the Centers for Disease Control and Prevention's Opioid Overdose Website

Source: CDC/NCHS, National Vital Statistics System, Mortality. Deaths are classified using the International Classification of Diseases, Tenth Revision (ICD–10). Drug-poisoning deaths are identified using underlying cause-of-death codes X40–X44, X60–X64, X85, and Y10–Y14. Age-adjusted death rates were calculated as deaths per 100,000 population using the direct method and the 2000 standard population.

Overdose Death Rates Involving Opioids by Type, United States, 1999-2021

DR_Opioids

National Reports

Drug Overdose Deaths with Evidence of Counterfeit Pill Use — United States, July 2019–December 2021. Morbidity and Mortality Weekly Report September 1, 2023

Illicitly Manufactured Fentanyl–Involved Overdose Deaths with Detected Xylazine — United States, January 2019–June 2022. Morbidity and Mortality Weekly Report June 30, 2023

Drug Overdose Deaths Among Persons Aged 10–19 Years — United States, July 2019–December 2021.  Morbidity and Mortality Weekly Report December 16, 2022

A qualitative assessment of circumstances surrounding drug overdose deaths during the early stages of the COVID-19 pandemic. SUDORS Data Brief 2, August 2022

Overdose Deaths Involving Para-fluorofentanyl — United States, July 2020–June 2021.  Notes from the Field, Morbidity and Mortality Weekly Report September 30, 2022

Vital Signs: Drug Overdose Deaths, by Selected Socio-demographic and Social Determinants of Health Characteristics — 25 States and the District of Columbia, 2019–2020. Morbidity and Mortality Weekly Report July 22, 2022

Drug Overdose Deaths in 28 States and the District of Columbia: 2020 Data from the State Unintentional Drug Overdose Reporting System. SUDORS Data Brief 1, June 2022

Characteristics of Adults Aged ≥ 18 Years Evaluated for Substance Use and Treatment Planning - United States 2019.  Morbidity and Mortality Weekly Report June 10, 2022

Notes from the Field: Xylazine Detection and Involvement in Drug Overdose Deaths — United States, 2019. Morbidity and Mortality Weekly Report September 17, 2021

Trends in Nonfatal and Fatal Overdoses Involving Benzodiazepines — 38 States and the District of Columbia, 2019–2020. Morbidity and Mortality Weekly Report August 27, 2021

Vital Signs: Characteristics of Drug Overdose Deaths Involving Opioids and Stimulants — 24 States and the District of Columbia, January–June 2019. Morbidity and Mortality Weekly Report September 4, 2020

Variation in Adult Outpatient Opioid Prescription Dispensing by Age and Sex — United States, 2008–2018. Morbidity and Mortality Weekly Report March 20, 2020.

Changes in Opioid-Involved Overdose Deaths by Opioid Type and Presence of Benzodiazepines, Cocaine, and Methamphetamine — 25 States, July–December 2017 to January–June 2018. Morbidity and Mortality Weekly Report August 30, 2019

Drug Overdose Deaths Involving Cocaine and Psychostimulants with Abuse Potential — United States, 2003–2017. Morbidity and Mortality Weekly Report May 3, 2019

Drug Overdose Deaths Among Women Aged 30-64 Years---United States, 1999-2017 Morbidity and Mortality Weekly Report January 11, 2019

Contact Information:
Allison Lake
Drug Overdose Prevention Epidemiologist, Division of Trauma and Injury Prevention