Janet Holcomb 2017-present
Governor Eric Holcomb
Karen Pence 2013-2017
Governor Mike Pence
Cheri Daniels
2005-2013
Governor Mitch Daniels
Maggie Kernan
2003-2005
Governor Joe Kernan
Judy O’Bannon
1997-2003
Governor Frank O’Bannon
Susan Bayh
1989-1997
Governor Evan Bayh
Joanne Orr
1981-1984
Governor Robert Orr
Elizabeth Bowen
1973-1981
Governor Otis Bowen
Patricia Whitcomb
1969-1973
Governor Ed Whitcomb
Josephine Branigin
1965-1969
Governor Roger Branigin
Virginia Welsh
1961-1965
Governor Matthew Welsh
Barbara Handley
1957-1961
Governor Harold Handley
Kathryn Craig
1953-1957
Governor George Craig
Helene Gates
1945-1949
Governor Ralph Gates
Maude Schricker
1941-1945,1949-1953
Governor Henry Schricker
Nora Townsend
1937-1941
Governor M. Clifford Townsend
Kathleen McNutt
1933-1937
Governor Paul McNutt
Martha Leslie
1929-1933
Governor Harry Leslie
Lida Jackson
1925-1929
Governor Edward Jackson
Katherine Branch
1924-1925
Governor Emmett Branch
Ella McCray
1921-1924
Governor Warren McCray
Cora Goodrich
1917-1921
Governor James Goodrich
Jennie Ralston
1913-1917
Governor Samuel Ralston
Lois Marshall
1909-1913
Governor Thomas Marshall
Eva Hanly
1905-1909
Governor Frank Hanly
Bertha Durbin
1901-1905
Governor Winfield Durbin
Kate Mount
1897-1901
Governor James Mount
Martha Matthews
1893-1897
Governor Claude Matthews
Rhoda Chase
1891-1893
Governor Ira Chase
Mary Ann Hovey
1889-1891
Governor Alvin Hovey
Cornelia Porter
1881-1885
Governor Albert Porter
Eliza Gray
1880-1881,1885-1889
Governor Isaac Gray
Nancy Williams
1877-1880
GovernorJames Williams
Eliza Hendricks
1873-1877
2nd Lady March 1885-November 1885
Governor Thomas Hendricks
Charlotte Baker
1867-1873
Governor Conrad Baker
Lucinda Morton
1861-1867
Governor Oliver Morton
Joanna Lane
1861
Governor Henry Lane
Mary Hammond
1860-1861
Governor Abram Hammond
Caroline Willard
1857-1860
Governor Ashbel Willard
Harriett Wright
1854-1855
Governor Joseph Wright
Louisa Wright
1849-1852
Governor Joseph Wright
Sarah Dunning
1848-1849
Governor Paris Dunning
Martha Whitcomb
1843-1847
Governor James Whitcomb
Ellen Bigger
1840-1843
Governor Samuel Bigger
Zerelda Wallace
1837-1840
Governor David Wallace
Catherine Noble
1831-1837
Governor Noah Noble
Esther Ray
1825-1831
Governor James Ray
Ann Hendricks
1822-1825
Governor William Hendricks
Deliah Boon
1822
Governor Ratliff Boon
Ann Jennings
1816-1822
Governor Jonathan Jennings