Hepatitis B 2004

Table 1. Hepatitis B Cases by Race and Sex, Indiana, 2004

  2004 2000-2004
Cases Rate* Cases
Total 80 1.28 405
   White 58 1.05 270
   Black 12 2.19 84
   Other 1 0.63 3
   Not Reported 9 - 48
   Male 56 1.82 279
   Female 24 0.76 126
   Not Reported 0 - 0

*Rate per 100,000 population based on the U.S. Census Bureau’s population data as of July 1, 2004

Hepatitis B is a serious viral disease of the liver transmitted by direct contact, including sexual contact, with blood or body fluids that contain the virus. Transmission can also occur from an infected mother to her infant in utero or at birth. The hepatitis B incidence rate for Indiana in 2004 was 1.28 acute cases per 100,000 population.

A comprehensive strategy was developed and implemented in the 1990s to eliminate hepatitis B in the United States. The strategy includes the following: screening all pregnant women for hepatitis B infection with the provision of postexposure prophylaxis to infants born to infected women; routine vaccination of all infants and children <19 years; and targeted vaccination of individuals at increased risk of hepatitis B including health care workers, dialysis patients, household contacts and sex partners of persons with chronic hepatitis B infection, recipients of certain blood products, persons with a recent history of having multiple sex partners or a sexually transmitted disease, men who have sex with men, and injecting drug users.

In 2004, there were 80 reported cases of acute hepatitis B in Indiana: 60 percent exhibited jaundice and 26 percent were hospitalized. No cases resulted in death.

Figure 1 shows reported cases of hepatitis B for the five-year period 2000-2004. In 2004, there was a 12 percent increase in reported cases of acute hepatitis B compared to 2003. Although there were cases throughout the year in 2004, the highest number of cases occurred during the late summer and winter months (Figure 2).

Cases of acute hepatitis B infection varied with age. Figure 3 shows incidence rates of acute hepatitis B cases per 100,000 population by age group. Nationally, higher rates of hepatitis B disease continue among adults, particularly males 25-38 years of age and persons with identified risk factors (i.e., injection drug users, men who have sex with men, and persons with multiple sex partners).

In 2004, 79 persons with acute hepatitis B were interviewed about risk factors for contracting the disease. Not all of those interviewed responded to each question asked. Table 2 highlights identified risk factors for 2004 Indiana cases. Nationally, the proportion of heterosexuals reporting multiple sex partners and self-identified men who have sex with men has increased in the past decade.

In 2004, 22 Indiana counties reported cases of acute hepatitis B. The incidence rates were highest among the following counties reporting five or more cases: Porter (4.5), Vanderburgh (4.0), and St. Joseph (3.0) (Figure 4).

Indiana law requires the reporting of both acute and chronic hepatitis B infections during pregnancy and perinatally exposed infants. In 2004, 125 Indiana women were reported as having infectious hepatitis B during pregnancy. Identifying these women during pregnancy facilitates appropriate medical treatment for infants.

You can learn more about hepatitis B by visiting the following Web site: