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Keep your patients safe by staying up-to-date on the latest health news, information, and vaccination recommendations.

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Resources
CDC Travel Health Clinical Updates

The Centers for Disease Control and Prevention (CDC) Yellow Book is the recommended resource for information specific to illnesses associated with a returned traveler. Visit the Yellow Book for general information on how to approach travel-related health problems.

As many as 43%–79% of travelers to low- and middle-income countries become ill with a travel-associated health problem. Although most of these illnesses are mild, some travelers become sick enough to seek care from a health care provider. Most post travel infections become apparent soon after returning from abroad, but incubation periods vary, and some syndromes can present months to years after initial infection or after travel. Additional resources for evaluating a returned traveler can be found here.

lllnesses associated with fever appearing in the first two weeks after travel
Syndrome Possible Cause

Systemic febrile illness with initial nonspecific symptoms

Malaria
Dengue
Typhoid fever
Rickettsial diseases (such as scrub typhus, spotted fevers)
East African trypanosomiasis
Acute HIV infection
Leptospirosis
Ebola virus disease
Viral hemorrhagic fevers

Fever with central nervous system involvement

Influenza
Bacterial pneumonia
Acute histoplasmosis or coccidioidomycosis
Legionella pneumonia
Q fever
Malaria
Tularemia
Pneumonic plague
Middle East respiratory syndrome (MERS)
Polio

Fever with respiratory symptoms

Influenza
Bacterial pneumonia
Acute histoplasmosis or coccidioidomycosis
Legionella pneumonia
Q fever
Malaria
Tularemia
Pneumonic plague
Middle East respiratory syndrome (MERS)

Fever and skin rash

Dengue
Chikungunya
Zika
Measles
Varicella
Rickettsial diseases (such as scrub typhus, spotted fevers
Typhoid fever
Parvovirus B19
Mononucleosis
Acute HIV infection

The Yellow Book covers common travel-related health problems, including fever in returned travelerspersistent travelers’ diarrhea, skin/soft tissue infections , and advice on screening asymptomatic returned travelers.

Clinics must be pre-authorized to administer the yellow fever vaccine. Please visit the link below to complete the application to become a YF provider. You will be contacted by IDOH after completing the application.

Page last reviewed/updated: March 2025